先(xian)恭賀(he)中國(guo)農業(ye)大(da)學譚(tan)鵬老師使(shi)用(yong)恒(heng)遠生物自主品(pin)牌ELISA試劑(ji)盒在(zai)《Nano Today》權威期刊上發(fa)表的SCI文獻(xian)——Manipulation of hydrophobic motifs ａnd optimization of sequence patterns to design high stability peptides against piglet bacterial infections順利通過(guo)，IF影(ying)響因子高達18.962分！其次恭(gong)喜譚(tan)鵬老師(shi)成(cheng)功贏取了恒遠(yuan)生物獎(jiang)學金(jin)，也感謝(xie)譚(tan)老師(shi)對恒遠(yuan)生物的信(xin)任與支持。
【文獻(xian)標題】Manipulation of hydrophobic motifs ａnd optimization of sequence patterns to design high stability peptides against piglet bacterial infections
【關鍵(jian)詞】Antibacterial biomaterials ,High stability ,Manipulation of hydrophobic motifs ,Optimization of sequence patterns ,In vivo efficacy
【DOI】//doi.org/10.1016/j.nantod.2023.101793
【影響因子(IF)】18.962
【出(chu)版期刊】《Nano Today》
【產品原文(wen)引用(yong)】
Healthy female weaned piglets (Duroc × Landrace × Large white, weighing ≈ 8 kg) were randomly divided into four groups (5 per group). One group of healthy piglets received no treatment ａnd served as a control. Piglets in the other three groups were intraperitoneally injected with 15 mL of E. coli ATCC25922 with an OD600 = 0.15, ａnd 2 h later, they were given an intraperitoneal injection of saline, peptide HLFP-5 (2.5 mg/kg), or HLWP-4 (2.5 mg/kg), respectively, with an injection volume of 10 mL. After 12 h, all piglets were euthanized. The blood of all piglets was collected ａnd the levels of inflammatory factors in serum were determined by the ELISA method. The inflammatory factor kit was purchased from Shanghai Hengyuan Biological Technology Co., Ltd. Partial livers, kidneys, spleens, ａnd lungs of bacteria-infected piglets were collected for bacterial enumeration studies by standardized localization. Furthermore, some organ samples of piglets were stained with H&E for histological examination.
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